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BETA CATENIN
Descriptors Found:
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DeCS
Descriptor
English
:
beta Catenin
Descriptor
Spanish
:
beta Catenina
Descriptor
Portuguese
:
beta Catenina
Synonyms
English
:
Catenin, beta
beta-Catenin
Tree Number:
D12.776.091.249
D12.776.220.145.500
D12.776.930.130
Definition
English
:
A multi-functional catenin that participates in
CELL ADHESION
and nuclear signaling.
Beta catenin
binds
CADHERINS
and helps link their cytoplasmic tails to the ACTIN in the
CYTOSKELETON
via
ALPHA CATENIN
. It also serves as a transcriptional co-activator and
downstream
component of WNT PROTEIN-mediated
SIGNAL TRANSDUCTION
PATHWAYS.
History Note
English
:
2006(1992)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
50821
Unique Identifier:
D051176
Occurrence in VHL
:
Similar:
DeCS